iClone

is very awesome - you can animate realistic 3D people. It comes with two free people and two sets, and you can buy waaaaaaaaay more. The fact that I  don't like to spend money has given me limits, but if you're a spender you can animate anything.

One note: Iclone is awesome in everything except for price and facial animation. If you get "CrazyTalk" from the same makers, you can import CrazyTalk files into iClone and make your characters talk like they aught to. Haven't tried it because I don't really need to, but if you want to make it seem more realistic get CrazyTalk.

both programs brought to you by...